Mobile genetic elements (MGEs, also called transposable elements, TEs), which can transpose from one location to another within the genome, are known to be one of the causes of large scale genome reorganization [ 1].
The Wembley saga could still go either way: it could become a national treasure, sweeping away all this grief, or it could remain a cause of large-scale moaning.
However, in order to involve businesses and investors in the process, a common understanding must be established that maximizing return on investment (ROI) per hectare is the main cause of large-scale degradation.
Investigating some 17 million single nucleotide variants from genomes of 562 tumors, it was shown that differential DNA repair, and not mutations, is the primary cause of large-scale regional mutation rate variations across the human genome [38].
Shigella dysenteriae serotype 1 (Sd1) has been identified as the cause of large-scale dysentery outbreaks, which are often associated with high attack rates (AR) and case fatality ratios (CFRs) [1] [5].
In the United States of America (USA), NoV has been shown to be a major cause of large-scale food poisoning [ 9], and the US Centers for Disease Control and Prevention CDCC) reported that NoV was detected in up to 96% of all viral gastroenteritis cases during the period from 1996 to 1997 [ 10].
The constantly increasing demand on quarries harms the general structure of the earth thus causing the emergence of large scale environmental problems.
The new spatial knowledge of temperature regions will also help the evaluation of possible causes of larger scale climatological changes in a biological context including productivity.
If we assume perfect rationality and complete markets, we are debarred from exploring the causes of large-scale economic failures.
However, as recent floods in Brazil and Australiaia – have shown, cities can be vulnerable to natural disasters, epidemics and other causes of large-scale social breakdown.
