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Furthermore, although cells of similar fluorescence intensity tended to be spatially clustered in culture (Fig. 5), no systematic link to flask location or confluence was evident to implicate cell microenvironment as the principal cause of expression heterogeneity.
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Two pages later, he remarked that "No doubt as long as man and all other animals are viewed as independent creations, an effectual stop is put to our natural desire to investigate as far as possible the causes of Expression.
In The Expression of the Emotions in Man and Animals, Darwin ([1872], p. 12) wrote 'as long as man and all other animals are viewed as independent creations, an effectual stop is put to our natural desire to investigate the causes of Expression.
Therefore, to track the causes of expression variations it is necessary to interrogate multiple types of molecular aberrations concurrently.
eQTLs include SNPs resulting in RNA splicing variations, which have been shown to be one of the underlying causes of expression differences and phenotypic diversity.
These data indicate that the negative association between LINC00173 and stemness gene sets observed in the guilt-by-association approach is indeed the consequence and not the cause of LINC00173 expression.
In the aftermath of the Charlie Hebdo massacre, PEN, an international association of writers dedicated to the cause of free expression, decided to honor the publication.
Thus, we sought to identify the cause of mCherry expression in these cells.
Altered gene coexpression networks have been proven to be the major cause of dysregulated expression during cancer progression [ 21, 22].
Several studies have identified RNA degradation to be a major cause of microarray expression measure variability [ 4, 6, 9- 12].
They acquire specific epigenetic marks in the parental germ lines which are the cause of monoallelic expression after fertilization.
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