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The World Health Organization has classified headache as the 14th cause of disabling illnesses.
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Neurodegenerative and cerebrovascular diseases are the most common causes of disabling cognitive impairment in late life.
It demonstrates the need for population-based prospective research that will investigate the causes of disabling low back pain and depression in the general population.
Environmental problems comprise a large segment of disabling skin disease.
Among elderly (≥65 years) individuals, musculoskeletal diseases were the main cause of disability due to their high prevalence and moderate disabling impact, while cardiovascular diseases were also an important cause of disability because of their moderate prevalence and high disabling impact.
Apart from any relation to cancer, cotton dust is a proven cause of the disabling respiratory disease, byssinosis.
Mental diseases are a leading cause of disability, and the World Health Organization estimates that one in four people will develop a disabling mental disorder during their lives.
Headache disorders are common disabling conditions that, in the last Global Burden of Disease study, were rated as the sixth cause of disability [1].
As a common disabling primary headache disorder, the migraine has been ranked as the third most prevalent disorder and seventh-highest specific cause of disability worldwide [1].
A new Stanford University School of Medicine study of twins suggests that non-genetic factors play an unexpectedly large role in determining autism risk, turning upside down recent assumptions about the cause of this common, disabling developmental disorder.
The R52L mutation in the RBD may cause structural rearrangements disabling the interaction of the PtdIns(4,5 P2 binding site in the CRD with membranes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com