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Alcohol was the leading cause of burden of disease for Australians under the age of 45 in 2011; alcohol-use disorders were responsible for 1.5% of the total burden of disease.
ClinicalTrials.gov NCT00479271 Recent estimates show that dementia is a major cause of burden of disease amongst the elderly in developing countries[1].
In 2010, the epidemic remains the number one cause of burden in 21 countries and the number two cause of burden in seven others.
Depressive disorders are a leading cause of burden of disease worldwide [ 1].
Alcohol is the third leading cause of burden of disease worldwide.
Research indicates schizophrenia is a cause of burden for patients and caregivers.
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In a review study on global burden of disease in 2013, migraine and mild-to-moderate mental disorders such as depressive and anxiety disorders were main causes of burden in this category for the Korean public [2].
MD ranks fifth among leading causes of global disease burden including developing countries, and by year 2030 it is predicted to represent one of the three leading causes of burden of disease worldwide [1], [2].
In 26 other countries, HIV/AIDS is among the top five causes of burden but not the leading cause.
HIV/AIDS and road injuries are the only top 10 causes of burden that are concentrated in young adults.
Furthermore, congenital anomalies are of the top 20 list of leading causes of burden of disease (DALY´s) and are an important contributor to infant mortality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com