Sentence examples for cause of attrition from inspiring English sources

Cardiovascular safety concerns are a significant cause of attrition in the development of new drugs (Lasser et al., 2002).

Drug toxicity is a leading cause of attrition of candidate drugs during drug development as well as of withdrawal of drugs post-licensing due to adverse drug reactions in man.

LTFU is the commonest cause of attrition, followed by death, which is often under-estimated [10].

In Buhera loss to follow-up remains the major cause of attrition (70% at 30m).

Loss to follow-up was the major cause of attrition, followed by death.

After 12 months on ART, the retention rate flattens, with loss to follow-up being the main cause of attrition.

Health-related mortalities were the most prevalent cause of attritions (Table 2).

The causes of attrition are unknown, but remodeling processes due to chronic overload that are reflected as bone marrow edema-like lesions (BMLs) on magnetic resonance imaging (MRI) might predispose the subchondral bone to subsequent attrition.

A major causes of attrition in the clinic is lack of drug efficacy [2].

The causes of attrition are complex.

There is historical precedence that industry can identify and remedy significant causes of attrition; inadequate drug metabolism and pharmacokinetics are no longer the primary cause of compound attrition.