No-one was injured, but the incident resulted in the withdrawal of all Merchant Navy class locomotives from service whilst the cause was ascertained.
Death from any cause was ascertained through the Washington State Death Certificate Data Files.
Mortality information, including ∼5,200 deaths coded as diabetes being the underlying cause, was ascertained by linkage to the Canadian Mortality Database from 1991 to 2001.
Hospitalisations for CVD were identified, using 20 diagnosis and procedure fields in hospital records, while death from CVD as the underlying cause was ascertained from the ABS cause of death data.
All discontinuation causes were ascertained by electronic and clinical reports (see Table 1 for categories besides the adverse event definition).
Incident cases of endometrial cancer and deaths from all causes were ascertained, respectively, by means of computerised record linkages to the Canadian Cancer Database and to the National Mortality Database.
Incident cases of colorectal cancer and deaths from all causes were ascertained, respectively, by means of computerised record linkages to the Canadian Cancer Database and to the National Mortality Database.
Deaths from all causes were ascertained by active follow-up through transplantation centre, medical centres that referred patients to the transplantation centre and family physicians.
Incident cases of renal cell cancer and deaths from all causes were ascertained, respectively, by means of computerised record linkages to the Canadian Cancer Database and to the National Mortality Database, both of which are maintained by Statistics Canada.
Incident cases of breast, endometrial, ovarian, colorectal, and lung cancer and deaths from all causes were ascertained respectively by means of computerised record linkages to the Canadian Cancer Database and to the National Mortality Database.
