Exact(7)
Therefore, publication of this manuscript will not in any way cause gain or financial loss or otherwise to any organization/institution.
It is important to recognise that most mutations affecting splicing factors such as SF3B1, U2AF1, and SRSF2 are more likely to cause gain of functions, 9, 33) indicating that they are unlikely to function as tumor suppressors.
Adapting at low backgrounds is inherently dangerous as statistical fluctuations in photon absorption introduce substantial noise into the neural signals accessible to a gain control mechanism; such noise would be expected to cause gain to vary widely.
Some p53 mutations cause gain of function that is independent of any complex formation with wild-type p53 and is associated with selective proliferative advantage (Gurova et al, 2003; Scian et al, 2004).
From our results no conclusion can be drawn if the single mutations in both mutants cause gain or loss of function of LRS1 as a regulatory element in high light adaptation.
As a result, the expression of genes where CISs are inferred to cause loss of function was positively correlated with metagene score (e.g. MYT1L), whereas the expression of genes where CISs are inferred to cause gain of function (e.g. TGIF2, Additional file 2: Figure S1) was negatively correlated.
Similar(52)
From 1898 to 1899 the Dreyfusard cause gained in strength.
The turning point was the 2-1 win at Blackburn a month later and suddenly a lost cause gained life.
The cause gained momentum in the past year as at least three people died and more than a thousand were sickened by contaminated tomatoes, lettuce, peanut butter and spinach.
This cause gained momentum just after World War II and, through coups, dictatorships and oppressive regimes, stretched to, and beyond, the first democratic elections in South Africa.
By tapping into distinct high school experiences, Schrode's cause gained traction.
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