The reason for this still remains unknown, several factors relevant to this polymorphism, such as different populations, different skin types [ 4] and differently damaged levels of apoptotic mechanisms, might cause different outcomes.
That is, while studies have demonstrated that interlocks created by executive directors compared to interlocks created by outside directors cause different outcomes at the corporate level (e.g., Geletkanycz and Boyd 2011; Tuschke et al. 2014), research on the determinants of interlock creation has ignored this difference so far.
For example, pathogens may affect hosts differentially (e.g., Johnson et al. 2012), cause different outcomes under different environmental conditions (e.g., Mitchell et al. 2005), and evolve increased or decreased virulence over time (e.g., Boots et al. 2004).
CR-driven research directs researchers to understand 'what works for whom, when, and why and explore the complex ways in which interventions interact with people, professionals, and settings to cause different outcomes' (27).
The fact that we do indeed recognize distinct modes of acute and chronic toxicity, and that agents cause different outcomes from short and prolonged exposures, argues against the generality of the needed assumptions for additivity to background (Rodricks et al., 2007).
In this study, we report that differences in synaptic properties, which were of no consequence under ordinary conditions, caused different outcomes when the circuit was challenged with an injury.
Taking together the differences in morphology, antigen expression and survival, we hypothesize that the composition of the expanded mMSCs (e.g. significant amount of nonproliferating osteoprogenitors) rather than the source of the population (mMSC or hMSC as discussed in [24]) causes different outcomes after transplantation.
These conditions were chosen based on their causing different outcomes in TMP treatment: only in minimal medium the treatment results in growth arrest, supplementation with both AA and Ad leads to cell killing, and addition of thymine rescues cells from the effects of the drug [ 15].
It is also important to recognize that different PCB congeners exert their effects via different mechanisms and can therefore cause different health outcomes [17], [49].
To get this knowledge we need a "more detailed understanding of how different combinations and levels of resources, and their associated opportunity costs, cause different patterns of outcomes" in different populations and contexts [ 12].
