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Mutations of tau cause dementias such as frontotemporal dementia and AD.
Since amyloidogenic peptides are believed to cause dementias (Hardy & Selkoe, 2002), transgenic mice carrying mutant APP, PSEN1/ 2 or BRI2/ ITM2b are used to model these dementias, as over-expression is necessary to reproduce amyloidosis (Jucker, 2010).
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Although a bad lifestyle can cause dementia in many people, it is more complicated than that.
Stewart is utterly unequivocal that repeated blows to the brain while playing can cause dementia, and the disease chronic traumatic encephalopathy, formerly known as punch-drunk syndrome.
"What is worrying is the fact that obesity levels are now rising alarmingly and are therefore liable to cause dementia levels to rise far beyond previous estimates".
While Alzheimer's is the most common form of dementia, other diseases that cause dementia are also characterised by the abnormal build-up of proteins in the brain.
"We need to be cautious at this early stage and our latest results do not demonstrate that low vitamin D levels cause dementia.
But did you know that stress can cause dementia-like symptoms?
Other conditions that can also cause dementia include Creutzfeldt Jakob disease (CJD), Huntington's disease, Lewy body disease, Parkinson's disease, vascular dementia, and Wernicke Korsakoff syndrome.
Among viruses that infect the brain, HIV-1 (human immunodeficiency virus type 1) is the most likely virus to cause dementia.
Moreover, CAA and cerebrovascular disease (CVD) may set a lower threshold for AD-like changes to cause dementia and may even cause dementia on its own, since patients with AD and CAA and/or CVD appear to be more cognitively impaired than patients with only AD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com