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Although this implies that blocking the KV current would be expected to cause more depolarization and a larger elevation of [Ca2+]i in PA than in MA, it is apparent that this depolarization in itself is not enough to cause constriction, since 4-AP alone, while enhancing agonist-induced constriction, does not directly constrict either PA or MA.
Of the autonomic nerve fibres the sympathetic fibres cause constriction of blood vessels, and the parasympathetic fibres cause their dilation.
Oversupply of O2 to arteriolar walls may cause constriction and paradoxically reduced capillary perfusion.
And insulin resistance has been show to cause constriction of the blood vessels to the scalp.
The vasoconstriction reported in this study supports previous work suggesting kisspeptins cause constriction of several, but not all, human blood vessels [11], but we were unable to assess the contribution of Kiss1R activation to vasoconstriction due to the unsuitability of p234 as an antagonist.
The interactions between side chain tryptophans and main chain amides cause constriction in the backbone resulting in this unwounding region.
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Infections can cause constrictions of the cervix, which may lead to difficult labour.
Nevertheless, when pre-constricted with U46619/ l-NAME/ODQ, both 1 and 10 μmol/L LY83583 still caused constriction in PA, and 10 μmol/L still caused relaxation in MA.
In healthy volunteers, subcutaneous injection of sumatriptan caused constriction of the STA, MMA, and MCA [39].
Subcutaneous injection of sumatriptan reduced headache intensity and caused constriction of only the extracranial arteries.
Fentanyl causes constriction of the sphincter of Oddi, but the contraction caused is weaker than that caused by morphine [14].
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