Pathological GRN mutations found to date cause disease as a function of haploinsufficiency, with mutations producing a premature termination of the coding sequence being largely to blame.
For these reasons, in a redefinition of the concepts of virulence and pathogenicity of microbes, Casadevall and Pirofski suggested a classification system for pathogens based on their ability to cause damage as a function of the host's immune response [ 58].
The longitudinal data related to outcomes will allow the estimation of cause-specific and all-cause mortality as a function of adherence (and persistence).
Finally, we assess the ability of these agents to inhibit cell proliferation and to cause cell death, as a function of pHe.
We also examined the concordance between the official and the revised cause of death as a function of time since diagnosis: patients who died within five years after diagnosis, patients who died after 5 years but before 10 years of follow-up and patients who died after 10 but before 15 years of follow-up.
Figure 2 shows likelihood of an outbreak being confirmed as caused by norovirus as a function of the number of specimens tested.
This study examines relationships of multiple causes of death as a function of factors available on the death certificate (demographics of decedent, place of death, type of certifier, disposal method, whether an autopsy was performed, and year of death).
The purpose of this article is to examine some straightforward relationships of multiple causes of death as a function of factors available on the death certificate (demographics of decedent, place of death, type of certifier, disposal method, whether an autopsy was performed, and year of death).
The top three graphs in figure 5 show how the crude probabilities of death due to treatment-related CVD, breast cancer death (excluding the CVD deaths) and other causes respectively vary as a function of time since diagnosis for patients diagnosed in 1992 at ages 55, 65 and 75.
