This genetic architecture potentially causes a serious issue for the quantitative arguments we have made about the spread of thrifty alleles (Speakman, 2006), and it might well be that this structure identified by GWAS is compatible with, and hence indirectly supports, the TGH.
The notification icon on your phone will not cause any serious issue if left unresolved.
For example, (Stranger et al., 2007) used 2 million single-nucleotide polymorphism (SNP) and more than 13 000 transcripts, leading to more than 10 tests for all possible associations, a number that causes a serious multiple testing issue (i.e. the chance of false positives in a family of multiple hypothesis tests is higher than that of a single test).
The toxin can cause liver damage when ingested — a serious issue not just for Toledo, but for millions of Americans that really upon the lake for drinking water.
Moreover, current data suggest that GalNAc-T3 is an ideal therapeutic target with minimum risk of side effects, a nontrivial consideration, as adverse reactions caused by anticancer agents are a serious issue in clinical management.
Ever since the first report of edwardsiellosis in 1959 [ 1], the mass mortality of fish caused by this bacterium has been a serious issue in aquaculture [ 2].
But the article raises a serious issue: whether drilling has caused unhealthy levels of radium in our drinking water.
Deforestation remains a serious issue in many countries, causing large-scale air pollution, loss of biodiversity, and affecting the livelihoods of local people.
Recent comments by some Japanese cabinet members, however, seem to reflect a growing sense of urgency to prevent the Futenma issue from causing a serious rupture in the relationship with the United States, Japan's longtime protector.
"If it was ever used in salt water, and some of them were, that can cause some serious issues".
