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The phrase "cause a negative effect" is correct and usable in written English.
You could use it when describing a change in a situation that had a negative outcome. For example, "The new policy caused a negative effect on working hours."
Exact(9)
In this case, we're talking about a study that was actually intended to cause a negative effect in many people, and one open question is how destructive it was in the worst instances that might have occurred.
Although the varied stocking densities (SD) applied presently had no impact on the survival rate (SR), increasing the stocking density but within this safe range may still cause a negative effect on the bioeconomic mechanism.
Accordingly, agglomerated/aggregated nanoparticles cause a negative effect on the modulus of nanocomposites.
HAWTs are very sensitive to the changes in wind direction and to the turbulence phenomena which cause a negative effect on their energy performance.
A dose at lower potency could cause "a negative effect almost immediately," he says.
Raising the total phenolics content, however, may cause a negative effect on apparent quality of the fruit.
Similar(51)
The prevailing ambient solar radiation caused a negative effect on plant growth and yield.
The increased C N ratio and the amount of inoculum yielded a positive effect while the increase of the temperature caused a negative effect on biodegradation.
The estimation of KS using the median method to estimate 1/KS was much better than the direct estimation of KS, causing a negative effect of non-linearity of KS in the kinetic equation.
This student loan overhang may be causing a negative effect on home buying, net worth growth, and even marriage and family formation.
The gap in depth between the assumed fault model and the true slab geometry causes a negative effect in the inversion results.
More suggestions(18)
cause a detrimental effect
cause a damaging effect
pose a negative effect
causing a negative effect
consequence a negative effect
caused a negative effect
cause a synergistic effect
cause a hypochromic effect
cause a negative impact
cause a negative contrast
cause a negative mood
cause a negative perception
cause a similar effect
cause a negative signal
cause a chilling effect
cause a negative appraisal
cause a complex effect
cause a negative market
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com