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Instead, it will cause a major anti-American backlash in China.
That birth will probably cause a major deterioration in the lifestyle of everyone affected.
But a credit downgrade is unlikely to cause a major shock to the system.
If that is not the case, that could cause a major tax problem.
It's unlikely a single ship getting stuck in ice will cause a major deviation in researchers' findings.
But the bigger question is whether it can cause a major upheaval in the UK and European gas market?
That's almost bound to cause a major bear market in stocks, with the Dow heading toward 3,600.
"Instead, we've got a garage that's too big, that will cause a major disruption and that will adversely affect the quality of life in town.
"Look at any disaster - unless it's caused by a terrorist bomb, it's normally down to a number of factors which, taken individually, would not cause a major problem".
Then there is the problem of unknown unknowns: the event that may cause a major move in the market may be one that no one has even spotted.
Experts say an all-out ban on carry-on luggage is unlikely because it could cause a major backlash from the lucrative business-travel segment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com