In the US, prescription opioids have caused a huge problem since oxycodone – better known by its brand name OxyContin – was licensed for use outside cancer treatment in the mid-1990s.
A quick web search reveals that, on the most popular landlord forums, the growth in zero-hours contracts is causing a huge problem for the (also fast expanding) private rented sector.
Inadequate food storage is causing a huge problem of food wastage in parts of India.
In this case, allocation, which should be a facilitating rule of ESF action, is transformed into a restrictive rule.......what happens here is that some streets are not listed, so this causes a huge problem for us here and for the users, who want to make appointments here and can't.
If one band member is causing a huge problem for the rest of the band, tell him/her that if they don't fix it, they'll be kicked out.
These breasts will cause Daenerys a huge problem; you can see it coming, and, saliently, you've seen it before, during desert starvations and circling enemies, never mind widowhood and 1,000-degree 1,000-degree.
Giving evidence about a Sunday Mirror story in March 2003 that claimed their marriage was in trouble, he said the disclosure caused a "huge amount of problems".
It has caused a huge amount of problems.
MBS's problems have caused a huge jump in multifamily loan delinquencies in Texas.
This is going to cause some huge problems in the not-so-distant future as it shifts its smartphones over to QNX too.
