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Amino acid substitutions introduced into query variants that reduce the similarity (calculated using substitution matrix BLOSUM62) of protein sequence to the functional homologs are considered to cause a damaging effect.
Similar(59)
The N-terminal part of occludin has an important role in a TJ assembly; this activity was revealed by an experiment in which abnormal occludin that lacks N-terminal domain caused a damaging effect on the TJ function of endothelial cell monolayers in vitro.
It was having a damaging effect on democracy, Shane said.
Technology has had a damaging effect on adolescents.
This has had a damaging effect on the animals that depend on the reef, such as crabs, turtles and nearly 600 species of fish.What is causing such ecological change is a matter of much debate.
That kind of relentless pressure has a damaging effect on adolescents.
Futterman argues that in team sports like basketball this has a damaging effect.
The form was having a damaging effect on the urban scene, she said.
Their refusal to think and act responsibly is having a damaging effect on world markets.
The prohibition, meanwhile, is expected to have a damaging effect on the economy.
But the RAC said government cuts in safety campaigns had had a "damaging effect".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com