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This can cause a big problem for the City during heavy rain or snowfall, because it is hard for the system to handle such a big flow, and with sewage in the mix it can be problematic.
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A senior Japanese negotiator today said that it had come under intense diplomatic pressure to soften its stance at the UN climate talks in Cancún and admitted that it was causing a "big problem" for the negotiations.
This causes a big problem for distributing the educational institutions according to the rules of population census.
Despite bailing them out (and practically owning some of them), the UK government seems unable to force high street banks to begin lending to small businesses again and this is causing a big problem for the economy — the wheels of capitalism won't grease themselves.
That causes a big problem for organizations.
A rush for the exits could cause a big problem across the debt markets.
These adverse effects cause a big problem.
Suddenly discovering there are twice as many badgers as you'd previously planned for clearly causes a big problem.
"That caused a big problem," recalled Evans.
By taking advantages of the competitive dispersion of GNRs, the developed method could effectively reduce false results caused by undesirable aggregation, which is a big problem for spherical gold nanoparticles.
Is that a big problem for you? A. It has not caused any inconvenience in administration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com