Exact(3)
To a lesser extent, imbalances inherited from a phenotypically normal maternal parent were also considered since the rearrangements may be causative without necessarily translating into similar abnormal GU traits in the female genitourinary tract.
Maternally inherited copy changes were included in this latter category as the rearrangements may be causative without necessarily translating into similar abnormal GU traits in the female genitourinary tract.
Given the limited amount of DNA sequence obtained for association mapping within many of the genes we investigated, we cannot positively identify these particular polymorphisms as causative without further investigation.
Similar(57)
Chemotherapy is the treatment of disease using chemical agents that are intended to eliminate the causative organism without harming the patient.
Secondly, the etiologic agents harboring plasmids have the potentials of disseminating antibiotic resistance and their associated plasmids to other causative agents without plasmids that were previously sensitive to the commonly used anti-conjunctival agents in Lagos.
The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation.
Detection of a causative polymorphism without the need for outcrossing, as necessary in classical mapping strategies, would therefore significantly extend the range of available methods.
Research should be directed towards the development of ultra-fast diagnostic techniques that can immediately predict causative microorganism, without the need of specimen processing and also detect multirresistance mechanisms to avoid inadequate initial antibiotic treatment.
Until further cases are encountered, allowing better characterization of the clinical manifestations associated with R. aeschlimannii infection and considering the agent capable of inducing either MSF or ATBF-like manifestations is crucial; neither of these syndromes can be associated with a specific causative agent without microbiologic identification.
Preceding the publication of these guidelines, numerous peer-reviewed articles suggested variants analyzed by IT to be causative/pathogenic/disease-causing, without confirmation of the predicted splicing effect.
MLPA was used to search for genomic copy number variations in 32 patients without causative mutations found after sequencing of 316 IRD genes.
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