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In this report, we review the inextricably link of serum uric acid to known cardiovascular risk factors, and we describe the possible mechanisms and potential causative role between serum uric acid and cardiovascular events in the general population, in subjects with cardiovascular risk factors and in those with pre-existing cardiovascular diseases.
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Collectively, these data suggest that future studies aimed identifying the association between, and, the causative role of gut bacteria and their related metabolic products on influencing physical function in older adults are of interest.
The authors speculate that, rather than playing a causative role in GDM risk, the association between first-trimester adiponectin and GDM reflects underlying insulin resistance that is already present early in pregnancy.
Significantly, it has been shown that interactions between the pathways play a causative role in several of these conditions (Ayyanan et al., 2006; Rodilla et al., 2009).
While its causative role remains uncertain, accumulating evidence suggests a correlation between high levels of IL-17 production by Th17 cells and steroid-resistant disease 52.
Variation in dispersal within a population is most probably due to the interaction between genetic and environmental causes (Dingle 1991) making it difficult to attribute a causative role for either.
Further field evidence for the causative role of TBT can be derived from the highly significant relationships between TBT body burden and the prevalence of genital excrescences in male and female dog-whelks.
Because previous studies demonstrated that human leukocyte antigen HLA-B27 has a causative role in AS pathogenesis, we subsequently investigated whether there is interaction between the ERAP1 SNPs and HLA-B27 positivity.
Our previous study demonstrated a crosstalk between Arg-II and S6K1 pathway which plays a causative role in eNOS-uncoupling and acceleration of endothelial senescence and age-associated vascular dysfunction [ 4].
31 The correlation between the telomere length and the occurrence of IPF suggests the causative role of shortened telomeres in IPF.
Moreover, neutralization of TNFα blunted HFD-induced differences in glucose tolerance between myeloid-specific Fas knockout and control mice, further supporting a causative role for TNFα in the observed phenotype.
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CEO of Professional Science Editing for Scientists @ prosciediting.com