Sentence examples for causative pathway from inspiring English sources

Despite great progress, a direct causative pathway from the HD gene mutation to neuronal dysfunction and death has not yet been established.

Therefore, such techniques are useful when the expressions of many genes of an important, causative pathway change.

Further cell and neurobiological studies are warranted to elucidate whether the CFH and the LOC387715 genes indeed belong to a common causative pathway.

A tentative gene-gene interaction between the two major AMD-associated loci, LOC387715 and CFH, was found in this study using a multiplicative (logistic regression) model, a synergy index (departure-from-additivity model) and the mutual information method (MI), suggesting that a common causative pathway may exist for these genes.

Metabolic changes associated with obesity are a possible causative pathway for OA [ 13].

These are also intermediate variables, in the causative pathway between the exposure and the outcome.

Mendelian diseases, the ones that Dr. Grant has linked to his set of synaptic genes, are mostly rare and obscure, but they may turn out to overlap with the common mental diseases in terms of their symptoms and causative pathways, in which case some treatments might overlap too.

There is a heritable component in IBS, and genetic research is a valuable tool for the identification of causative pathways, which will provide important insight into the pathophysiology.

Indeed, recent work has continued to resolve the unique cellular lineages, and causative pathways responsible for ectopic bone development yielding promising avenues for the development of novel therapeutic strategies shown to be successful in analogous animal models of HO development.

No inferences about causative pathways between IBS and perceived food intolerance can be made.

And we encourage research that identifies causative pathways of the spread of infectious disease and other health threats.