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The important bacterial pathogens responsible for causing diarrhea are diarrheagenic Escherichia coli, Salmonella typhi, Bacillus cereus, Campylobacter jejuni, Aeromonas hydrophila, Shigella spp., Yersinia spp., and Vibrio cholera, and the main causative parasites in contaminated domestic water supplies included Giardia intestinalis and Cryptosporidium parvum [ 10].
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Africa was the region of the world most affected by river blindness; more than 37 million people worldwide were infected with the causative parasite, Onchocerca volvulus, and many of these individuals lived in poor rural African communities.
Toxoplasma gondii is the causative parasite of an important worldwide disease.
Pfmrk is a Cyclin Dependent protein Kinase (CDK) from Plasmodium falciparum, the causative parasite of the most lethal form of malaria.
A library of 1,4-benzodiazepines has been synthesised and evaluated for activity against Trypanosoma brucei, a causative parasite of Human African Trypanosomiasis (HAT).
Trypanosomal phosphodiesterases B1 and B2 (TbrPDEB1 and TbrPDEB2) play an important role in the life cycle of Trypanosoma brucei, the causative parasite of human African trypanosomiasis (HAT), also known as African sleeping sickness.
In the present work, thirty-one N2,N4-disubstituted quinazoline-2,4-diamines that had not previously been examined for their antileishmanial activity were evaluated for their potency and selectivity against Leishmania donovani, the causative parasite of visceral leishmaniasis.
Distinct modes of transmission characterize the two causative parasite species responsible for VL.
A Cochrane review on the treatment of New World CL found that 4 out of 38 trials failed to mention the causative parasite [ 70].
To improve strategies for controlling transmission of the causative parasite, Plasmodium falciparum, we require a thorough understanding of the developmental mechanisms, physiological processes and evolutionary pressures affecting life-history traits in the mosquito.
Although we were unable to speciate the causative parasite as being Fasciola hepatica or F. gigantica in this particular clinical study, other veterinary and malacology studies conducted in the region and East Africa in general [ 19, 22, 23] have shown the presence of both species.
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