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"I wasn't thinking this would be the causative molecule until I talked to Vikas," he said.
Because TTR was the only candidate protein identified in mass spectrometry, we hypothesized next that the causative molecule would not be a protein.
Certain mediators, with TNF as one causative molecule, can be successfully targeted in the treatment of chronic arthritis.
It is hypothesised (but still under debate [ 142]) that Aβ is a causative molecule of AD by inducing neuronal cell death and concomitant disturbance of synaptic function.
In our study, EGFR expression was closely associated with extensive lymph node metastasis with high ND, suggesting that the EGFR might be a causative molecule for such aggressive phenotypes.
As the majority of samples contain ≥50%% of their compounds identified with match qualities of 89 50 or <50%%, a specific BEN causative molecule or molecules may also be among these compounds, or among the hundreds of compounds present in lower concentrations than addressed in this study.
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As LNM is considered as an important prognostic factor for GC [ 29], research of the causative molecules reflecting LNM is a promising avenue to improve the outcomes.
Despite enhanced HIS as determined by hyperinsulinemic-euglycemic clamp (HEC) studies, no further characterization has been performed to identify the causative hepatic molecules or pathway for this finding, thereby leaving a gap in the understanding of hepatic PANDER action under both fasting and fed conditions.
A more complete understanding of the pathogenesis of DN may allow identification of causative and related molecules that could be useful as diagnostic markers.
Although IgG4 is a central feature of IgG4-RD, the recent discovery of IgG4-negative IgG4-RD raises questions about the causative role of the IgG4 molecule in this context.
The apparent distinction between alleles that predispose their carriers to and those that offer protection in T1D incriminates HLA molecules themselves as causative factors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com