Sentence examples for causative hypothesis from inspiring English sources
The association between radiation effects and the free-radical theory of aging as the causative hypothesis seems to be more compelling than that between radiation and the nutrient-sensing TOR pathway.
The risk factors included in this study have all been associated with credible underlying causative hypotheses, and confounding has been taken into account for a large number of factors, but the effect of their elimination cannot be precisely estimated in the absence of this information.
Thus, our algorithm is effective in suggesting potential causative gene hypotheses that the user can examine for biologically interesting possibilities to follow up on.
A likelihood ratio score is then calculated between each of the three alternative models (as null hypotheses) and the causative model (as an alternative hypothesis), whereas the three respective p values are calculated on the basis of a theoretically derived distribution of the likelihood ratios.
Based on this knowledge, we formulated a testable hypothesis that causative arginine variants will impact EGFR autophosphorylation and Stat3 phosphorylation.
The last explanation, under the hypothesis of causative microbial agent, is that this agent is a no viable or uncultivable bacteria or fungi.
The overall conclusion of the researchers was that a single locus was causative, but an alternate hypothesis is that an unlinked locus is present in A6 which acts in conjunction with the SACPD-C deletion to elevate stearic acid content beyond the 10-15% threshold.
This case demonstrates that keratitis may lead to keratoconus-like corneal changes and supports the hypothesis of a causative link between recurrent inflammatory process and the development of keratoconus.
The justification of this double approach arises from the different hypothesis about the causative mutations underlying each method.
According to the amyloid hypothesis, a major causative factor in the development of Alzheimer's disease (AD) is the presence of extracellular plaques that contain amyloid-β.
The most common approach is to identify genes whose eQTL colocalize with QTL of interest, providing new functional hypothesis about the causative mutation.
