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Therefore causative connections between complex I inhibition by metformin, and the physiological consequences of metformin treatment, remain contentious.
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A causative connection between the vaccinations and the paralytic syndrome was never proved.
Previous studies have shown that synteny breakpoints between the mouse and the human genomes are enriched in human segmental duplications, suggesting a causative connection between such structures and evolutionary rearrangements.
This clearly suggests a causative connection between molecular perturbation and observed phenotypic similarity in these relationships.
Our recent study further revealed a causative connection between dysfunctional telomeres and the cryptic splicing of lamin A [ 19].
Studies on these models provided further evidence for a causative connection between OPA1 mutations and ascending RGC death, making ADOA a true neurodegenerative disease.
To show a direct causative connection between flotillin depletion and EGFR expression levels, we performed rescue experiments by stably re-expressing EGFP-tagged flotillins in the knockdown cells.
A causative connection between theses two conditions has never been postulated, but is suggestive enough in this case to hypothesize it.
Similarly, the causative link between one time LSD use and chronic psychosis is relatively weak.
Although the current literature does not support a causative association between isotretinoin use and depression, there are important limitations to many of the studies.
However, a causative association between viral agents and VKH disease has not yet been established.
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