Sentence examples for causal testing from inspiring English sources

However, such studies do not allow for a functional or causal testing of newly identified candidate genes.

The unscaled latent variable can hardly provide useful information to the causal test.

Thus, to provide a causal test of the climbing fiber role in VOR learning, and to analyze climbing fiber-induced plasticity over a longer time scale, we used an optogenetic stimulation approach in mice.

In those circumstances, definitive causal hypothesis testing would require a study that uses prospective cohort design.

For example, 6% of adipose meQTLs are also associated with gene expression in adipose tissue (32), while causal inference testing (CIT) has identified 10 CpG sites that mediate genetic risk for RA through effects on gene expression (31).

The two populations were generated separately with different phenotypic means (μA and μB) and different causal and test SNP MAFs (pA = 0.2 and pB = 0.4 for both causal and test SNPs).

This rich source of information is now being exploited by various procedures like dynamic causal modelling to test hypotheses about neuronal circuits in health and disease.

This variable was used as genotype (G) in the causal inference tests.

EWAS: Epigenome-wide association study; EOC: Epithelial ovarian cancer; CTCs: Circulating tumor cells; LD: Linkage disequilibrium; CIT: Causal inference test; DNAm: DNA methylation; PCA: Principal components analysis.

In a manner similar to that described in Liu et al. [ 16], genotype (G), methylation (M), and phenotype (Y) relationships were assessed using the causal inference test (CIT) [ 45] to classify them as "methylation mediated", "methylation consequential" or "independent".

A causal inference test at 16 years further indicated that the child's own overweight is a mediator in the suggested association between maternal BMI and offspring asthma at 16 years.