This has clear public health implications that services for different categories of developmental disorders should not be segregated prematurely and health systems need to consider overarching programmes to fill the gap for all developmental disorders.
In males, major functional GO categories included metabolism, biosynthesis and transcription, whereas enrichment of female DEGs upregulated by MSG feeding again fell into the categories of developmental and anatomical structural function.
Thus the expansion and evolution of LCA faces four main categories of developmental challenges: establishing mechanisms and models; gaps in data and knowledge; incorporating temporal and dynamic components; and comparability limitations derived from differing on scenarios and system boundaries.
From qPCR experiments, we found differential expression of ESTs belonging to the main categories of developmental arrest during diapause, and identified additional ESTs from pathways that have not yet received attention in previous studies on the molecular bases of diapause (Table 7).
Instead, DSM-III introduced the category of 'pervasive developmental disorders', a diagnosis that included four sub-categories, namely 'infantile autism', 'childhood onset pervasive developmental disorder', 'residual autism' and an atypical form (J. C. Harris, 1998: 1998.
In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) [ 6], a category of pervasive developmental disorders in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) [ 7] has been converted to a new category of ASD in which ASD severity is quantitatively rated according to current difficulties.
As defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), autism falls under the broad diagnostic category of Pervasive Developmental Disorders and is marked by impairments in communication, forming relationships/social interaction, and often behavioral control [ 10].
Gene ontology analysis of differentially expressed genes indicated enrichment of categories representative of developmental pathways (Table S2).
The health of caregivers of children with CP will be used as a prototype, to demonstrate the application of the proposed theoretical framework within the broader category of 'developmental disabilities'.
