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As 135 patients could not be categorized with certainty ("undetermined") formal calculation of sensitivity and specificity was precluded.
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Moreover, this study highlights the challenges of statistical analyses using small, endogamous groups to study a phenotype that is: (a) incompletely penetrant, (b) variable in expression and (c) by its very nature, difficult to categorize with certainty.
Changing the recommendation for women aged 40 49 from a B grade to a C grade suggested that the USPSTF had incorrectly categorized the certainty of the mammography in the past (i.e., it went from high/moderate certainty to uncertain).
The scientists cannot say with certainty now".
No one can predict with certainty.
He spoke with certainty.
"With certainty," I said.
It is difficult to say with certainty.
This I can say with certainty.
No one can say with certainty why.
"Oranges," he said with certainty.
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CEO of Professional Science Editing for Scientists @ prosciediting.com