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The categorized candidate variables were then each fit as categorical predictors in separate single predictor logistic regression models predicting 28-day mortality.
We categorized candidate regions into those eight classes manually.
This summarized information offers a useful source of categorized candidate genes for systematic functional analyses of common metabolic/biochemical pathways or regulatory pathways, whereas genomic annotation in RAP-DB or MSU RGAP projects do not provide systematic information associated with putative function assigned to a gene.
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In addition, SNPs categorized as candidate functional SNPs were selected from each LD bin.
Before examining effect modification, we categorized each candidate gene into a dummy variable so that the gene and the pollutant of interest only have one interaction term.
Consequently, genes with fold changes < 1.46 from zero across all 384 arrays were categorized as candidate endogenous reference genes and were ranked according to ascending values of SD of Log ratio (Table 1).
Next, we functionally categorized our candidates based on sequence homology to plant, yeast, or animal gene orthologs with known biological function (Additional file 5).
In viewing cellular localization of constructed colon proteome, we further categorized protein candidates into globular or membranous proteins based on amino acids hydrophobicity calculated by Kyte-Doolittle and Hopp Woods formula.
The RHObase server (Chakraborty et al. 2014) was used to categorize each candidate thermophilic ROox α-subunit into a similarity class and to obtain the closest biochemically characterized homologs.
Absorption is often predicted using the Biopharmaceutics Classification System, which categorizes the candidate drugs on the basis of their solubility and permeability.
The probeset was categorized as a candidate alternative exon.
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