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It is based on structural and functional categorizations of chemicals derived from decades of animal testing with a wide variety of chemicals.
The categorization function was derived from all trials in a particular test, and the slope was estimated by logistic regression.
With regard to temporal bracketing, a visual mapping strategy was used to describe events in each period, in particular to verify the categorization scheme that initially derived from the literature review.
The categorization of economic status was derived from the economic classification criteria drafted by the Brazilian Advertising Association, which classifies the population into five socioeconomic categories based on the educational level of the head of the household, consumer goods owned (e.g., VCRs, DVDs, color TVs) and access to household help [ 10].
The categorizations of defensive actions taken are derived from those used by SharkRepellent.net.net
The approach-bias is then derived from reaction-time (RT) differences between these two categorizations.
For further categorization of the miRNAs, alignments were performed with miRNA sequences derived from S. japonicum and miRNAs from other organisms using the ClustalW 1.8 program[ 22].
The cut-off value representing the best discrimination derived from the ROC analysis was chosen for categorization of metric variables (LDH (lactate dehydrogenase) and expression of Mcm2).
This categorization is described in detail in an earlier study on breastfeeding derived from this cohort [ 14].
In the following the main results derived from both samplings are summarized according to the functional categorization of target genes: Characteristically, S. aureus expresses adhesins in the early stages of growth, whereas toxins are produced in the late stages.
These broad categorizations are important as many of the relationships found in the Comparative Toxicogenomics Database are derived from animal models.
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