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Future work can be expected by addition of other species, further gene family inferring approaches or even another categorization systematic: the technical background of O2EM is in principle capable to visualize gene groups beyond a categorization in families.
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Our results added to those from the literature, showing a categorization and a systematic analysis of REFs and confirming that the REF design plays a key role in rank learning.
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It was not possible to do a systematic categorization of those who declined.
The phylogenetic classification of single-domain TFPs presented here serves to illuminate the patterns of relatedness among currently known single-domain TFP families and should provide a general basis for a more systematic categorization of novel TFP members.
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