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In summary, prognostic categorizations using clinical guidelines identify a subgroup with a remarkably low rate of distant metastasis.
Standards and design guidelines recommend categorization of these structures based on their importance, safety function that they have to perform, hazard class, etc.
Furthermore, the American College of Radiology (ACR) has published reference guidelines on the categorization of breast tumors according to their ultrasound characteristics [ 14].
In Germany, both the Federal Joint Committee (G-BA) and the IQWiG have clear guidelines on the categorization of risk of bias for individual studies, while the latter excludes studies with high risk of bias from its own analyses.
This categorization is recommended by Japanese CKD guidelines [ 17].
However, the small cell sizes that resulted after this categorization did not meet MES confidentiality guidelines.
Categorization was based on US obesity guidelines with 30% or more body fat being considered obese, 25-31% acceptable, 21-24% fitness, and 14-20% athletic for women [ 30, 31].
We used the NCCN risk categorization from 2007, because the current guidelines are not solely based on clinicopathological factors that are commonly available.
We used US Preventive Services Task Force (USPSTFS) and Medicare eligibility guidelines to determine appropriate categorizations for age.
34 The 2010 European Society of Cardiology guidelines largely dispensed with categorizations of high, medium, and low risk.
The obese and overweight categorization follows the Body Mass Index (BMI) guidelines for Spain [ 39] (see Additional file 1).
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