To allow for a lag in the effectiveness in some of the above interventions, we categorised the data to include periods immediately before and after intervention.
19 However, a recent Canadian study of 3290 THRs did categorise BMI to include a morbidly obese group (BMI>40 kg/m) and although the authors found no difference in time to revision between BMI categories in an unadjusted analysis, there was a marginally significant difference for septic revisions.
Propositions categorised here include words such as "influence", "need" and "require".
Alcohol consumption has previously been considered as a confounder 10 and, being a potentially important lifestyle factor available from primary care data, 29 was categorised and included in the analyses (light (≤2 units/day), medium to heavy (≥3), ex-use or no use).
The quality assessment process, using the brief quality of reporting assessment criteria developed by the authors and used elsewhere [ 49], was also found to be fit for purpose for this review: The reviewers independently and consistently categorised each included study in the same way, as either adequately or inadequately reported.
All variables were coded into dichotomised values except age, which was categorised according to the included cohorts: 60, 66, 72, 78, 81, 84, 87, 90 and 93 years.
There are eight categorised climbs including the classic, exposed ascent of Holme Moss.
Saturday's penultimate stage is the race's queen stage and features five categorised climbs, including an ascent of Alpe d'Huez.
Studies were categorised as "included" or "excluded".
