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This problem is exacerbated by the current lack of a community-defined consensus set of categorisation criteria, or even a consensus naming system, for multi-domain RPs.
It may be worthwhile reconsidering current categorisation criteria (NHS Non-operative Diagnosis Subgroup of the National Coordination Group for Breast Screening Pathology, 2001; Perry et al, 2006) and potentially modifying the B3 category into two risk-based subgroups (B3 with lower probability of cancer, B3 with higher probability of cancer).
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The expert panel agreed that these classification criteria should be applicable only to people with symptomatic disease because the prognosis of asymptomatic disease is presently not well delineated in the literature, and to enable categorisation based on features of symptomatic episodes.
Table 1 presents the independent variables used in the univariable and multivariable linear regression analyses, methods and instruments used for data collection and criteria for categorisation of the variables.
Recent literature is unanimous in making the point that categorising continuous predictors should be well justified and motivated, and that, if necessary, the selected criterion for categorisation should be objective and sufficiently validated.
Bank of Italy inspectors use this categorisation as one of the criteria for determining which bank accounts to inspect.
Whilst it has been suggested that differences in heritability estimates reflect the ease of categorisation according to the scoring criteria and therefore smaller diagnostic variation [10], an additional reason may be due to the low prevalence of abnormalities in traits 4 9 at the age of scoring.
It enquires about 14 common neurotic symptoms allowing categorisation according to ICD-10 criteria.
A systematic review of 12 priority-setting frameworks from 11 agencies in 10 countries highlighted differences across HTA agencies regarding categorisation, scoring and weighting of criteria [ 7].
We modified EQUIP study criteria 3 for error categorisation and severity classification by adding or clarifying severity criteria for all error categories, and by grouping errors into 10 distinct areas according to stage of the prescribing process (see below and table 2).
For 16 of the 18 criteria, agreement with the categorisation of the criteria into the high, intermediate and moderate categories was high at ≥ 70% (10 had agreement ≥ 80%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com