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Here, we investigated the clinical outcomes in the FREEDOMS study and its' extension, by categorical change in T2LV.
Every subject in this series had at least one site on lateral STG that demonstrated either an increase in HGB power during SV compared to PB, or a categorical change in HGB response type with an "onset" response during PB and a "sustained" response during SV.
Findings were supported by the analysis of categorical change.
Additionally, we also compared categorical change in the RSDI versus categorical change in the other health status measures.
Abbreviations: MPH, methylphenidate; PBO placebo, D, met categorical change definition for diastolic blood pressure; S met categorical change definition for systolic blood pressure; P met categorical change definition for pulse.
These same results are presented again in an alternative format in Figure 3, showing categorical change in the RSDI versus categorical change in the other health status measures.
Similar(30)
Categorical changes, such as MADRS response and remission, were analyzed with the Cochran-Mantel-Haenszel test.
Categorical changes in lipids are also reported separately based upon protocol-specified fasting collection methods.
Categorical changes in PPBC scores were analyzed using chi-square tests.
Longitudinal mean changes and categorical changes (temporal patterns) were assessed via a likelihood-based repeated measures approach.
The incidence of categorical changes in aspartate transaminase (AST) was similar to changes in ALT (data not shown).
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