Sentence examples for catastrophic dysfunction from inspiring English sources

For us, aging is the creeping and then catastrophic dysfunction of everything, all at once.

Axonal transport deficits are often suggested to govern the pathologies which characterize classic neurodegenerative disorders, with Alzheimer's disease as the archetypal pathology with dystrophic axons from such catastrophic dysfunction of the molecular transport machinery [ 121].

The increased vulnerability of trees to catastrophic xylem dysfunction under drought may contribute to the observed stunted growth and periodic stem-dieback of trees in metal-contaminated landscapes, the effects being exacerbated by the thin soils.

These data indicate that decreased complex activities are the primary underlying mechanism and the secondary increase of ROS reinforces vicious cycle and results in catastrophic mitochondrial dysfunction, including decrease in ATP production.

Obama no doubt knew that FEMA's response to Hurricane Sandy could be the difference between a second term and a President Romney, in addition to showing whether Fugate had managed to successfully rebuild an agency low on morale and high on dysfunction following the catastrophic response to Katrina in 2005.

When considering LETM1 haploinsufficiency, the consequent chronic mitochondrial hyperpolarisation in the context of elevated mitochondrial O2− production and mPTP dysfunction could conceivably have catastrophic implications for normal neuronal function.

Mr Kissinger told the BBC that doing nothing would be "catastrophic", and "would show a degree of dysfunction in our political system that would be very unfortunate".

The polling firm's Economic Confidence Index tumbled 12 points as Americans became more worried about congressional dysfunction, which could cause a catastrophic debt default by the U.S. government.

Sepsis with multiple organ dysfunction syndrome (MODS) is the most catastrophic manifestation.

Neurodegenerative diseases share common features, including catastrophic neuronal loss that leads to cognitive or motor dysfunction.

Although controversial initially, IAH is now widely accepted as a cause of organ dysfunction and ACS is recognized as a catastrophic disturbance of a patient's physiology that requires urgent intervention and guided therapies [ 6].