Exact(33)
This situation resembles an error catastrophe, i.e., the complete loss of biological information due to excessive noise and errors.
Indeed, many regulatory elements that control mitotic catastrophe, i.e. cell cycle-specific kinases (Cdk1, Plks, Aurora), cell cycle checkpoint proteins, survivin, p53 and p21waf1/cip1 could also be implicated in the regulation of death ligand expression (7, 29).
With environmental catastrophe I think it's the same".
"This is the full catastrophe," I say blearily.
"This is a catastrophe," I moaned to a friend at around the ten-minute mark.
"When I saw in Rome that catastrophe, I felt I had to be here.
Similar(27)
Despite the food catastrophes, I was really getting to like Susanne.
"Barring any catastrophes I think we have a good shot at winning an Olympic medal.
As for the assertion that someone with a gun might have prevented one of these recent catastrophes, I can think of two things to say.
Great DIY Disasters is a current favourite, and I am regularly contacted by young researchers seeking details of the most terrible building catastrophes I have come across.
3. Don't make everything a catastrophe- I just want to chuckle when people say "well I have to say this is the worst thing that has ever happened to me".
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