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Crystal structure of the catalytic core of human DNA polymerase kappa.
The catalytic core of the motor complex is a ring ATPase that consists of five subunits.
(H Crystall structure of the IN catalytic core dimer interface and the IBD of LEDGF/p75 (PDB 2B4J).
Khvorova, A., Lescoute, A., Westhof, E. & Jayasena, S. D. Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity.
"A hereditary spastic paraplegia associated atlastin variant exhibits defective allosteric coupling in the catalytic core". J. Biol.
Two of these subunits, p22phoxand gp91phox, are integral membrane proteins and form a heterodimeric flavocytochrome, also known as cytochrome b558, which constitutes the catalytic core of the enzyme.
Catalytic core and substrate specificity remains to be investigated.
In particular, most of the catalytic core shows greatly reduced cleavage.
The catalytic core of these ribozymes is formed by two structural domains.
Only the coordinates for the catalytic core domain were extracted from the PDB structure 2NYL.
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It folds into a similar 3-dimensional catalytic core structure with a 2-lobed structure.
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