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A typical cancer biomarker discovery workflow consists of a discovery phase, during which a comprehensive comparative catalogue of candidate proteins is generated.
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This report provides a catalogue of specific candidate genes that can be further expressed in heterologous systems in order to confirm their putative roles in mescaline biosynthesis.
In order to expand the catalogue of frequently methylated candidate TSGs in RCC we undertook an analysis of copy number and CpG methylation profiling of sporadic RCC.
We generated a candidate catalogue of 2R-paralogues using a reciprocal best-hits strategy between the amphioxus and Xenopus gene models, validated by phylogenetic reconstruction and examination of syntenic context.
The EST catalogue was examined for putative homologs of candidate genes involved in bud phenology, cuticle formation, phenylpropanoids biosynthesis and cell wall formation.
By 18 December, the team had published its results on the Internet: a catalogue of 323 distant galaxy candidates, along with their redshifts--a measure of distance and, hence, age.
The objectives of the present study are (i) to describe the transcriptomes of these four tropical genera, (ii) to compare expression profiles among species and organs (leaves, stems and roots), and (iii) to provide an initial catalogue of well-supported mismatches, as candidates for validation as SNPs.
Identifying proteins with conserved Met residues in the vicinity of known phosphorylation sites is certainly one approach to catalogue possible candidate proteins that might be regulated in this manner.
Within our catalogue of hypoxia-responsive genes are novel candidates for hypoxia-driven angiogenesis.
Homology-based cloning of candidate genes and their subsequent functional testing in heterologous expression systems are accelerating the pace at which the gene catalogues of alkaloid biosynthesis are expanding.
Haplotype scans were refined by imputation with the catalogue of sequence variation segregating in the CC to suggest potential candidate genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com