Although many companies are racing to develop computer programs that will catalog the sequences into databases, Shibata's team contends that using evolutionary biology's computational tools may actually help scientists explain the deeper meaning of the information.
Using six sets of cancerous and normal tissue samples taken from four colorectal and two breast cancer patients, the Johns Hopkins team used next-generation sequencing methods to catalog the genome sequence data of each patient.
Therefore it is important to catalog all the sequence differences between any two organisms so that these can be a basis for designing experiments linking phenotype to genotype.
Their ultimate goal is to catalog the COI sequence of every species on Earth.
By cataloging the coding sequence variations using these databases, we found that 4.36% of CVs from HGMD are concurrently registered in dbSNP (8.11% of CVs from dbSNP are concurrent in HGMD).
Therefore, we have developed the novPTMenzy database which catalogs information on the sequence, structure, active site and genomic neighborhood of experimentally characterized enzymes involved in five novel PTMs, namely AMPylation, Eliminylation, Sulfation, Hydroxylation and Deamidation.
Second, ORION-VIRCAT reconstructed in an object-relational format a genomic catalog mapping all the sequences from NCBI-VGR to the officially accepted naming developed by the ICTV.
The draft sequence makes available a comprehensive catalog of sequence differences between the CB4856 and N2 strains that will facilitate the molecular dissection of their phenotypic differences.
In this approach, we divide the total time interval Tc from 1923 to 2007 covered by the catalog into a sequence of non-overlapping and touching intervals of length T. The maximum magnitude M T,j in each T-interval is identified.
Liu et al. (2003) investigated the hypocenter catalog of the aftershock sequence following the 1993 Mw 7.3 Landers earthquake and concluded that only 5% of aftershocks occurred on the mainshock fault plane.
To our knowledge, this is the first study of its kind that reports a comprehensive catalog of sequence variation in the entire LPL gene in African individuals in relation to plasma lipid traits.
