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Interestingly, in a recent study from Moody et al. in New Zealand a similar observation was made, i.e., subjects with cat sensitization had increased nasal NO levels.
Although Leynaert et al. [ 41] found adults who had lived on a farm as a child had lower levels of cat sensitization and a lower risk of nasal symptoms in the presence of pollen, they found no consistent association between living on a farm in childhood and the risk of asthma or wheeze: a similar proportion had 'atopic asthma' in the farm and non-farm groups.
Similar(58)
An association between early exposure to cat and sensitization to cat has been shown by others [ 24, 25], but to our knowledge such comparisons have not been made for exposure to horse and sensitization to horse.
"The first year of life is the critical period during childhood when indoor exposure to dogs or cats influences sensitization to these animals," the study's authors concluded.
No such association was found for pollens or cats, although sensitization to house dust mite was slightly more frequent in those with severe asthma (OR 1.61) [ 16].
While we have suggested intrinsic differences in the groups, one could suggest that these groups are therefore not similar in other ways, unrelated to cat exposure and sensitization.
In most communities, avoiding cats in the home would not decrease the prevalence of sensitization to cats because cat allergen is distributed in schools, other public buildings, and homes without a cat.
Early exposure to cats appeared possibly to prevent sensitization to cat allergens in some children, although findings were inconsistent.
Several recent studies have reported that the prevalence of sensitization to cat is reduced when children live with one or more cats (Hesselmar et al. 1999).
There was a clear association between sensitization to cat and nasal NO, but there was no relation to current exposure to cat allergen.
Risk factors were selected among risk factors usually published in the literature, mainly age, sensitization to cat allergen, house dust mite, and molds, smoking habits.
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