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Despite these encouraging findings, two recent randomized controlled trials failed to produce overall survival benefit of increasing TMZ dose intensity by extended administration in recurrent and newly diagnosed gliomas, which casts concerns on the usefulness of this strategy.
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AOL Time Warner Chief Financial Officer Wayne Pace stuck by the company's targets for advertising revenue at its troubled AOL online unit a day after a top Internet analyst cast concerns on its online ad prospects.
Our results also cast serious concerns on the reliability of using Pax8 as a marker to identify pancreatic neuroendocrine tumors as proposed by Sangoi et al. (2011).
However, this regimen was associated with considerable non-haematologic toxicity of mucositis and vomiting, and high HDFL-induced neurotoxicity cast another concern on its safety.
Taken together, these concerns cast doubt on the potential of CMMB to alleviate the threat of extinction for most marine species affected by fisheries bycatch.
Any cast on will do.
But in 2007, a year before Operation Cast Lead, Ya'alon's concerns focused on the 1.4 trillion cubic feet of natural gas discovered in 2000 off the Gaza coast, valued at $4 billion.
So the president calmly states that there is no alternative to ratcheting up the pressure -- with war in full view on the table -- even though broadly cast talks on their concerns as well as ours never have been considered by Washington.
That is far too heavy a burden of proof because it is too easy to cast doubt on evidence concerning mental capacity.
But, alone among the states, Georgia requires a defendant to prove such a disability beyond a reasonable doubt a heavy a burden of proof because it is so easy for a state to cast doubt on evidence concerning mental capacity.
Patent experts said the case was "concerning" and cast doubt on Google's ability to defend Android partners.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com