Exact(21)
As explained in Section 7.2, in these cases sequence optimization (Section 6) yields an increased bandwidth implying a reduced effective oversampling factor Moversampling.
The sequence showed homology to putative GH20 proteins from ascomycetes such as Leptosphaeria maculans (CBX95932) and Trichoderma reesei (EGR50812), although in these cases, sequence identity levels were only about 30%.
Table 2 Prioritized test suites Strategy Test cases sequence Strategy 1 TC4, TC6, TC3, TC5, TC1, TC7, TC7 Strategy 2 TC7, TC4, TC7, TC3, TC6, TC2, TC2 Strategy 3 TC6, TC2, TC1, TC7, TC4, TC3, The The sequence of test cases proposed by the strategies.
In these cases, sequence alone cannot define the correct edges.
In nine cases sequence and genetic location data supported the manual assignment over that of Xref.
Phylogenetic analyses indicated that, in most cases, sequence differences between homologous len loci of the different L. interrogans serovars occurred after the evolutionary diversification of the loci themselves.
Similar(39)
In many cases the resolution was improved over ITS but in other cases sequences were too variable to align accurately and yielded phylograms inconsistent with other data.
Having seen the same variant twice in a small number of selected cases, sequence-specific genotyping was used on probands from the remaining sib pairs, as well as controls.
In few cases, sequences labeled as different DLX genes had identical homeodomain amino acid sequence.
In 9 cases, the sequence outcome now appeared identical to the mutation assay result and in 4 cases sequencing was unsuccessful due to poor DNA quality.
In such cases, sequencing, or an equivalent variant-discovery method, may be the only way to identify a disease association.
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