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This review will focus on the clinical and instrumental markers useful for the very early identification of AD monogenic cases, pivotal in the development, and evaluation of disease-modifying therapy.
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In parallel with numerical tool development, physical component testing utilising realistic load cases is pivotal in achieving a greater understanding of performance variations including the contribution of degradation mechanisms.
Thus, a very early identification of monogenic cases is pivotal in the development and evaluation of disease-modifying therapy needed also in the most common sporadic form.
For all of us, the Reeves Hill case is pivotal.
There is little question that Mr. Brown was the case's pivotal witness.
Hafetz calls the Marri case a pivotal test of "the most far-reaching use of detention powers" ever asserted by an American President.
Mr. Barrow's case is pivotal because, with the help of his lawyers, he has overcome an arbitration clause by using the fundamentals of contract law to fight back.
In any case, of pivotal importance for the evaluation of the vaccination strategies is the fact that, due to this early viral activity in São Paulo, there was not a significant difference in the overall timing of viral activity (as measured by the vector means of the distribution of the isolates) between both cities.
Today, Cooper is happy to cite the case as "a pivotal event in Second Amendment jurisprudence" that "ultimately became the guts of Scalia's Heller decision".
The court will hear back-to-back arguments next month in that case and another pivotal gay rights case that challenges the 1996 federal Defense of Marriage Act.
That many black people living in London were, as the duchess implies, "things", slaves who did not have full agency over their lives, is evident in the two pivotal cases presided over by Mansfield.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com