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In order to generalise our model, more cases of validation are needed.
Disease-free survival from 410 cases of validation dataset was displayed in Figures 1(a) and 1(b).
We then addressed the survival impact of clinical and molecular factors in 269 cases of validation group, with a median follow-up of 38 months.
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This was more or less true in the majority of cases, independent of validation and comparison, and independent of the agreement of the BLA with the other (inappropriate) methods.
Overall, 47/40 (DPEP1/SDCBP2) cases of the validation cohort 1 were used for further analysis.
In addition, this collection accepts cases of failed validation and negative findings, data that traditionally has been difficult to publish.
Sox11 immunoreactivity was nuclear and was observed in all cases in the population cohort and in 67 out of 72 cases of the validation cohort, ranging from 0.5%to94%4%.
The cases of the validation and the test sets are not used during training; thus these cases are unknown to the classifiers (unseen data).
A significant (P = 0.040) positive correlation of the methylation status also was obtained with MSP and qMSP in 12 samples (six negative and seven positive cases) of the validation set.
Random sampling of cases for validation was carried out separately in each of the three databases using a specific module in the Jerboa software designed for this purpose.
Another computationally intensive validation approach is leave one out validation, an extreme case of cross validation with partitioning to the total number of instances.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com