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Many cases of HAS are asymptomatic when they are diagnosed accidently, and the most common initial complaints are nonspecific symptoms such as right upper quarterant pain, fatigue, weakness, and weight loss [ 1], making it rarely diagnosed antemortem [ 1, 7].
The Shanghai study reported a male-to-female ratio of 2.0 1, so did a study of 6 consecutive cases of HAS from 2000 to 2005 in Ganzhou, PRC [ 26].
In order to identify cases of HAS reported in Taiwan, we also conducted a thorough literature search in the PubMed database using "angiosracoma" as the key word and review the articles retrieved.
A study in Shanghai, People's Republic of China (PRC) [ 25] found 6 cases of HAS in 5,487 consecutive cases of primary liver cancers from 1991 to 2005, which was higher than the proportion of 8 in the 40,832 cases from 1980 to1999 in a study in Taiwan [ 24].
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