Sentence examples for cases methylation of from inspiring English sources

Both the HpaII and MspI enzymes recognize CCGG sites [22], and in many cases methylation of cytosine residues in the restriction sites could not be detected between the two digestions, such as the occurrence of methylation of all four cytosine residues at the recognition site.

In selected cases, methylation of CpG sites within AJAP1 was confirmed using bisulfite sequencing.

Although DNA methylation is generally considered to be a repressive epigenetic modification, experiments presented by Hu et al. suggest that in some cases, methylation of a given promoter sequence can result in activation of transcription.

In this latter case, methylation of alkanes, as in iso-alkanes, could have decreased the solubility of the aliphatic compounds, which in turns would have rendered resistance to or discouraged biodegradation.

If this is the case, methylation of these loci may be useful for detection of former smoking behaviour.

In the former case, methylation of the side-chain reduces its acidity, giving rise to the observed shift in the p Ka for kFAD from 7.5 (l-Lys) to 8.1.

These results once again show how variations in the properties of the substrate can modulate the reactivity of a monooxygenase; in this case, methylation of the guanidinium moiety both finely controls the proton transfer events in NOS and tunes the oxidative chemistry of the hydroperoxoferriheme.

The present results again show how variations in the properties of the substrate can modulate the reactivity of a monooxygenase; in this case, methylation of the guanidinium moiety both finely controls the proton transfer events in NOS and tunes the oxidative chemistry of the hydroperoxoferriheme.

In the majority of cases, methylation patterns observed in medulloblastomas corresponded to the methylation status of the normal cerebellum.

In several cases, methylation affects the status of other post-translational modifications (PTMs) present on the target protein [ 72].

To further explore the relationship between the accumulation of methylation events and survival we divided the cases in three groups corresponding to cases with no methylated genes (n = 18), cases with methylation of 1 to 3 genes (n = 14), and cases with more than 3 methylated genes (n = 6).