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Using LIST69 and the reduced data, the differences of means of these combined scores were calculated in dependent t-tests (listwise exclusion of cases, level of significance 0.05).
The three platforms selected for the case studies differ by the type of key stakeholders (though R&D organizations and universities dominate in all cases), level of development of strategic documents and plans for their realization, and the ability to attract external funding for R&D.
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Lepra's Bangladesh study, the first of its kind, found that in some cases, levels of awareness were quite high, with 80% of those questioned understanding that leprosy was curable.
In all cases, levels of expression were higher in DBA/2J than in C57BL/6J mice.
In DLB cases, levels of Atg7 were moderately reduced compared to controls and AD cases (Figure 1A, D).
In some cases, levels of chromatin-bound H3K9me3 were higher in JMJD2B-depleted cells (Figure 5B and 5D).
In contrast, in the AD cases levels of Cathepsin D were elevated compared to non-demented controls (Figure S1A, C).
By immunoblot analysis, compared to controls and AD, in DLB cases levels of mTor were elevated and Atg7 were reduced.
Compared to non-demented controls and AD cases, levels of mTor and phosphorylated-mTor (p-mTor) were elevated in the brains of DLB cases (Figure 1A, C).
In contrast, in DLB cases levels of neuronal mTor immunoreactivity were increased (Figure 2C, G), while the levels of neuronal Atg7 immunolabeling were reduced (Figure 2F, G).
In all cases, levels of DO remained constant in the presence of chloroquine, an inhibitor of lysosomal degradation (Fig. 4B).
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