In both cases, indicator variables for days of the week were included in the models.
In the first case, indicators of internal quality of the communities are often not sufficient to ensure the quality of the results - think, for example, at the resolution limit that arises in modularity maximization algorithms [37, 38].
The main outcomes were decisions to 1) diagnose and 2) treat the cases, based upon the information presented, analyzed via binary logistic regression of the randomized factors and case indicators on diagnosis and treatment.
At the aggregate level, the assessment begins by identifying indicators of the relevant what-goals--in the biomedical case, for example, indicators of health.
For each outcome, we built an imputation model of tertiles of D-dimer levels, including the variables used in the proportional hazard model and the case-indicator.
Thus, we built the same linear prediction model for each Z2 based on the stratification phase-1 variable and the case indicator.
Under the rare disease assumption, we have shown that a simple generalized linear model, using all the complete data (cases and non-cases) and including the case indicator among the explanatory variables, has to be considered [ 10].
Practically, in addition to the case indicator and the stratification variables, when the subcohort was selected by stratified sampling, it is necessary to include in the imputation model all the variables appearing in the proportional hazard model.
The imputation model was: Z2 = α0 + α1 I case + α2 Strata + ε, where α0 and α1 are scalar, α2 is a vector coefficient, I case is the case indicator, Strata is the vector of stratum indicators and є is the vector of errors independently and identically distributed ~ N (0, σ).
Let τ j be the infection time and h j the index case indicator of individual j, with h j = 0 and τ j = 0 if j is an index case and h j = 1 and τ j > 0 otherwise, j = 1, …, N. Note that the infection time of an infected individual j can be observed only if τ j ∈ [ 0, T ].
