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In all cases, hazards could be eliminated by biologically plausible revisions, and in some cases, these revisions could be considered corrections to the biology in the model.
In multivariate analysis, HER2+ (versus HER2-) status was associated with poor BC-SS for non-T4 patient cases (hazards ratio = 1.16, 95% confidence interval 1.05 to 1.28) and had a borderline significant association with improved BC-SS for IBC (hazards ratio = 0.82, 95% confidence interval = 0.68 to 0.99).
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Air pollution was not associated with all diabetes cases (hazard ratio 1.00 [95% CI 0.97 1.04] per interquartile range of 4.9 μg/m mean NO2 levels since 1971), but a borderline statistically significant association was detected with confirmed cases of diabetes (1.04 [1.04–1.04]).
Women randomised to hormone therapy had significantly more abdominal aortic aneurysm events than controls in the Estrogen Alone trial (14 v 6 cases, hazard ratio 2.4) 20 and a number similar to controls in the Estrogen plus Progesterone trial (7 v 6, hazard ratio 1.1).
Univariate Cox regression analysis revealed that MET FISH-positive cases showed a significantly poorer outcome than negative cases (hazard ratio for progression and death in MET FISH-positive cases relative to MET FISH-negative cases, 3.83 (p = 0.008) and 2.25 (p = 0.03), respectively (Table 3).
[Figure 3] The association between timing of ART and death was only statistically significant, however, when comparing those that initiated ART within the first 120 days of TB treatment to those who started later: among bacteriologic-confirmed cases, hazard ratio [HR] 9.0, 95% confidence interval [CI] 1.1 73.0.
In that case, Hazard is the lead man, but he cannot carry this team on his own.
Such heterogeneity necessitates unique case-by-case hazard evaluation, risk assessment, and risk management.
Therefore, in the vast majority of cases, system hazards occur after the test result arrives back in the practice.
In some cases the hazards of transporting a patient could be prevented by performing diagnostic or therapeutic procedures within the ICU or choosing alternative (albeit equivalently effective) procedures that may render a transport of the patient unnecessary.
Moral hazard is all too real for many treatments, and in some cases, behavioral hazard reinforces it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com