Therefore, we incorporated two specific aspects of the distribution of case durations, namely, (1) the average case duration and (2) the percentage of case durations shorter than 1 h.
As this alteration might significantly change the distribution of case durations, we decided to include the average case duration and the percentage of case durations shorter than 1 h.
The other included factors namely, the number of cancellations due to prioritizing urgent patients, the average case duration, and the percentage of urgent patients were not significant.
This model indicated that the average case duration and the number of cancellations due to overrun of previous surgeries were significant factors (see Table 5).
It should be noted that the AMC ophthalmology department has a case mix with predominantly short case duration and is thus at greater risk of cancellations due to overruns.
> The total monthly overtime, the number of cancellations due to overrun of previous surgeries, the number of cancellations due to prioritizing urgent patients, the average case duration, and the percentage of case durations shorter than 1 h could be extracted from OKplus.
For example, the maximum utilization rate of an operating room was assumed to be a certain percentage (e.g., 85%), without taking a specific surgical case mix into account (e.g., the distribution of case durations and the percentage of urgent procedures).
Analysis has assessed the design of each study, in particular with respect to experimental design, number of cases, duration of treatment and tests used to evaluate drug clinical efficacy.
Variables studied in the model included the number of persons exposed per infected patient, secondary attack rate, percentage of atypical and subclinical cases, duration of preclinical infectious period, and infectious period, as well as case-fatality rate.
Additional sensitivity analyses explored the sensitivity of the base case scenario to changes in the values of key model parameters including the number of index cases, duration of infectious periods, and infectious contact rates.
